Safety is a core value present and regulated in every aspect and activity of the oil and gas industry. Similarly, the whole value chain of the industry should have a friendly and outstanding environmental performance, not only as a matter of principle, but keeping in mind the regulatory framework that pushes for ever more cleaner processes. In this regard, Mexico is prepared and aligned with international best safety and environmental practices to safeguard every activity involved in its oil and gas industry. Mexico’s Security, Energy and Environment Agency (ASEA) is in charge of regulating the country’s oil and gas industry by enforcing the legal framework and designing specialized guidelines for all activity that requires industrial safety and environmental performance. With this in mind, it is imperative that Mexico extends its track-record of industrial safety excellence, mostly developed by PEMEX, adding international best practices and recommendations from well-known institutions like the OECD, IEA and IEF. It must also continue to introduce and adapt international best practices regarding environmental performance and adhere to its international environmental commitments, like those signed at COP21.